Octet / Protecting Groups

tert-Butyldimethylsilyl

Included in Protecting Groups.

Source Details

Name

tert-Butyldimethylsilyl

Abbreviation

TBS or TBDMS

Protects

Alcohols

Install Reagents

TBSCl, imidazole, DMF

Remove Reagents

TBAF (tetrabutylammonium fluoride) or HF

Notes

Very common. Stable to many conditions. Removed by fluoride.