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Zaitsev vs Hofmann Products

Zaitsev vs Hofmann Products - organic chemistry study tip. Mnemonic: Zaitsev = "Z" for "Ze more substituted" alkene. Zaitsev (most substituted alkene) is favored with small bases. Hofmann (less substituted) is favored with bulky bases like KOtBu or with poor...

mechanism

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Topic

Zaitsev vs Hofmann Products

Mnemonic

Zaitsev = "Z" for "Ze more substituted" alkene

Tip

Zaitsev (most substituted alkene) is favored with small bases. Hofmann (less substituted) is favored with bulky bases like KOtBu or with poor leaving groups.

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