Octet / Reactions
Acyl Chloride Formation
Acyl Chloride Formation (Carbonyl.) Converts CC(=O)O to CC(=O)Cl using SOCl₂, or PCl₃, or PCl₅.
Carbonyl
Reaction details
Name
Acyl Chloride Formation
Type
Carbonyl
Starting Material
CC(=O)O
Product
CC(=O)Cl
Reagents
SOCl₂
or PCl₃
or PCl₅
Mechanism
- Smiles
CC(=O)O
- Description
Acetic acid
- Smiles
CC(=O)Cl
- Description
Acetyl chloride (most reactive carbonyl derivative)
Tips
SOCl₂ most common - gaseous byproducts escape
Acyl chlorides very reactive - use quickly
React with alcohols → esters, amines → amides
Related Reactions
fischer-esterification
This is one row of the Reaction roadmap sheet - print all 83 reactions on one page.