Octet / Reactions
Grignard Addition to Carbonyl
Grignard Addition to Carbonyl (Carbonyl.) Converts CC=O to CC(C)O using CH₃MgBr, then H₃O⁺. Conditions: Anhydrous ether, then acid workup.
Carbonyl
Reaction details
Name
Grignard Addition to Carbonyl
Type
Carbonyl
Starting Material
CC=O
Product
CC(C)O
Reagents
CH₃MgBr
then H₃O⁺
Conditions
Anhydrous ether, then acid workup
Mechanism
- Smiles
CC=O
- Description
Acetaldehyde
- Smiles
CC=O
- Description
Grignard (nucleophilic carbon) attacks C=O
- Smiles
CC(C)O
- Description
After acid workup: 2-propanol (secondary alcohol)
Tips
Grignard adds carbon nucleophile to carbonyl
HCHO → 1° alcohol; RCHO → 2° alcohol; R₂CO → 3° alcohol
Strictly anhydrous! Grignard destroyed by H₂O
Related Reactions
aldol-addition
This is one row of the Reaction roadmap sheet - print all 83 reactions on one page.